Stress pressure, fatigue, poor diet, excessive alcohol and drugs damage neural connections between the brain’s prefrontal cortex and the rest of the brain. Additionally, the brain bypasses its “higher,” more evolved, rational frontal executive circuits and it starts using more primitive stimulus/response pathways. Furthermore, under chronic stress, we tend toward rigid thinking, reactive behavior, distracted attention, worry, anxiety, and low self-esteem.
The stress (fight or flight) response releases adrenaline, noradrenaline and cortisol, which leads to faster heart rate, increased cardiac output and narrower arteries. So in our chronically stressed world, this translates into fatigue, high blood pressure, eating and sleeping disorders, a weakened immune system and a long list of stress related ailments. Not good, you say.